3 cases of endometrial cancer that endometrial cytology was negative but doubted in hysteroscope views

Abstract

Introduction: An endometrial polyp is a benign clinical finding, but distinguishing a polyp from a malignancy, such as endometrial cancer, can be difficult¹⁾ . We report three cases of endometrial cancer, the endometrial cytology was negative, but the definitive diagnosis was established hysteroscopic appearance.

Case 1-3: Three women were referred to our hospital for evaluation of an endometrial polyp or endometrial thickening. Every endometrial cytology was negative. We performed a hysteroscopy and suspected endometrial cancer based on nodular or papillary or polypoid tumor with abnormal surface vessels for each patient. We performed a hysteroscopic biopsy of the mass and an endometrial curettage to each patient. Every pathologic diagnosis were endometrioid carcinoma (G1/G2).

Conclusion: For an in utero mass which does not lead to a diagnosis based on images and examinations, such as a MRI of the uterus, hysteroscopy can facilitate the diagnosis.