Gastric-type adenocarcinoma of the uterine cervix diagnosed after laparoscopic surgery following preoperative diagnosis of lobulated cervical gland hyperplasia: A report of two cases

Abstract

  Most cystic lesions of the uterine cervix are benign; however, it is important to distinguish these from gastric-type adenocarcinoma, including minimal deviation adenocarcinoma. Although radical hysterectomy is the standard surgical procedure for cervical cancer, it is highly invasive and requires accurate preoperative diagnosis. We report two cases of gastric-type adenocarcinoma of the uterine cervix in patients who were preoperatively diagnosed with lobular endocervical glandular hyperplasia (LEGH) and underwent laparoscopic simple hysterectomy. These cases highlight the role of preoperative conization for cervical cystic lesions. Additionally, definitive diagnosis is difficult in patients with preoperative imaging findings showing LEGH; therefore, laparoscopic surgery should be carefully considered if malignancy cannot be ruled out. Gastric-type adenocarcinoma of the uterine cervix is rare, and a limited number of cases could be investigated at a single center; therefore, further multicenter large-scale studies are warranted to confirm our findings.