Abstract
Uterine myoma is one of the most common gynecologic benign tumors, and surgical treatment is often needed. Myomectomy is ideal for the reproductive-aged woman who desires to preserve fertility, and the laparoscopic approach is becoming increasingly popular as a minimally invasive and safe procedure. Because laparoscopic myomectomy is technically demanding, various researchers have reported criteria for the proper selection of patients for this procedure. Almost every study proposes a size of myoma as the most important exclusion criteria. In this study, we report three cases of laparoscopic myomectomies for large myomas. Precise pre-operative evaluation, GnRH analogue pretreatment, new port placement to establish a superior operative field, and pre-operative preparation of autologous blood for transfusion may enable laparoscopic myomectomy for large myomas to be a safe and feasible procedure.