Abstract
The aim of the present study was to evaluate the values of anti-inflammatory cytokines (IL-10) in the first trimester of pregnancy and its association with threatened preterm delivery. The subject group consisted of 149 pregnant women who delivered live infants at Showa University Hospital from January 2011 to July 2012. In this study, we measured and analyzed the IL-10 levels in two comparative conditions. As a result, in Comparison 1, there was no significant difference between the IL-10 levels of “preterm birth group” and “term birth group”. In Comparison 2, the IL-10 levels of those hospitalized due to threatened preterm delivery were significantly higher than the IL-10 levels of those not requiring early hospitalization. In conclusion, to determine the levels of IL-10 in first trimester maternal serum may have the potential to predict imminent preterm delivery from an early stage of pregnancy.
