Abstract
The internal pressure (∂E/∂V)T has a range of 0.2-2 GPa for pure liquids. Its effect on the rate and equilibrium constants of chemical reactions can be gauged approximately if the reaction can also be studied in the gas phase at the same temperature. The influence of internal pressure is not different from that of external pressure. A few examples are mentioned. The effect is unfortunately usually overshadowed by other solvent properties such as its ability to engage in hydrogen bonding and solvation of ions and dipoles.
