Abstract
In this article, development of organic synthesis using high temperature and high pressure water as a reaction solvent was described. This process used a microreactor system. The microreactor system contributed to increase the reaction yield by the quick heating from room temperature to reaction temperature. Therefore, the side reactions during the heating process were inhibited. As an example, the corrosive and explosive organic synthesis, aromatic nitration reaction, was studied. The special microreactor system lined the inner wall by the corrosion resistant material was applied. Some results of noncatalyzed nitration reaction were discussed.