The Review of High Pressure Science and Technology
Online ISSN : 1348-1940
Print ISSN : 0917-639X
ISSN-L : 0917-639X
Reviews - Towards Understanding the Mechanism of Biological Response to Pressure -
Deep-Sea-Inspired Chemistry: Harnessing Extreme Environments for Sustainable Innovation
Mikako TACHIOKA, Shigeru DEGUCHI
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2026 Volume 36 Issue 1 Pages 44-52

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Abstract

This article introduces the concept of “deep-sea-inspired chemistry,” which derives chemical innovation from the extreme physicochemical and biological conditions found in the deep sea. Three representative examples are discussed: (1) baroplastics that undergo pressure-induced order–disorder transitions, (2) bottom-up nanoemulsification mimicking hydrothermal vent dynamics, and (3) cellulases evolved in deep-sea microbes. These systems demonstrate how pressure, thermal gradients, and enzymatic function in deep-sea environments can inspire sustainable materials and processes. This approach proposes a paradigm shift in ocean utilization—from a resource economy to a knowledge-driven circular economy—highlighting the deep sea as a new frontier for chemical technology.

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