Abstract
The effects of pressure on the aggregation of swine erythrocytes were investigated by monitoring the erythrocyte sedimentation rate under high pressure, up to 40 MPa. The aggregation of erythrocytes in plasma was propor-tionally enhanced by pressure, whereas aggregation of erythrocytes was not observed in saline solution up to 40 MPa. These results suggest that the adhesion energy between erythrocytes is not directly affected by pressure, but through a change in the interaction energy between plasma components and erythrocytes.