Abstract
Contralateral risk-reducing mastectomy is a prophylactic treatment for breast cancer patients with hereditary breast and ovarian cancer syndrome (HBOC). Patients can elect to undergo this treatment based on the biological characteristics of BRCA-related breast cancer in order to reduce anxiety about secondary cancer development. In recent years, risk-reduction surgery has been reported to reduce the risk of developing new primary breast cancer by >90% and improve overall survival. As of 2020, prophylactic surgery is covered by public health insurance in Japan based on evidence of its efficacy and safety for the treatment of patients with hereditary breast and ovarian cancer. As BRCA1/2 genetic testing is also now covered by health insurance, the number of patients diagnosed with HBOC is expected to increase. Currently, the number of elderly breast cancer patients is increasing due to the aging population and progress in drug treatment. Therefore, it is necessary to respond to the needs of patients of a wide age range. Based on this background, we report a case of contralateral risk-reducing mastectomy for an elderly patient with HBOC who developed unilateral breast cancer.
