2023 Volume 23 Issue 1 Pages 17-21
Hereditary breast and ovarian cancer syndrome (HBOC) is one of hereditary tumor patients whose fertility is a problem. This disease is characterized by the onset of early-onset breast cancer, and it causes great conflict for patients in trying to balance both cancer treatment and pregnancy, both of which are time-constrained. Embryo cryopreservation, oocyte cryopreservation, and ovarian tissue cryopreservation are considered as possible fertility preservation treatment for HBOC patients with cancer. However, there are concerns about reduced ovarian reserve in patients with HBOC, and the debate is still ongoing. Currently, in Japan, evidence regarding fertility preservation treatment being reported. Especially in HBOC patients, it is essential to accurately assess individual patient's ovarian reserve and implement optimal fertility preservation treatment.