2023 Volume 23 Issue 2 Pages 50-54
One of the risk factors for bilateral breast cancer is the family history, and the experience cases of bilateral breast cancer are increasing due to the progress of diagnostic imaging, and the improvement of postoperative survival rate. The characteristics of metachronous bilateral breast cancer with the family history experienced in this hospital were examined. Among 48 cases of metachronous bilateral breast cancer experienced in our hospital from January 2014 to December 2016, 12 were cases with family history and 7 (58%) were first-degree relative. Metachronous bilateral breast cancers in first-degree relative had a large number of early breast cancers of stage0-1, and the hormone receptor was positive and HER2 negative. Patients with a first-degree relative for family history were 5 years younger than those who had no family history, and the duration of the first and second cancers was more 5 years. The local recurrence of group with a first-degree relative for family history was significantly higher than without family history (p= 0.001). For the patient of the younger generation with the family history, the long-term follow-up considering the metachronous bilateral breast cancer is necessary.
