Abstract
Objectives: A retrospective observational study was conducted to clarify the factors that could affect postoperative emergence or extubation time, analgesia or sedation in the patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods: After institutional approval, 425 consecutive patients were studied. Data were collected from patients' medical records, and the correlations were determined between emergence time, extubation time, time before giving analgesics or sedatives and age, gender or body mass index as patient factors, anesthetic dose of fentanyl, duration of anesthesia, fluid balance as anesthesia factors, and CPB time as a surgical factor. Multiple stepwise regression analysis was used, and a value P<0.05 was considered as significant. Results: Significant positive correlations were found between emergence time and age and CPB time, between extubation time and anesthesia time, CPB time and age. The time to giving analgesics correlated with age, CPB time and fluid balance. The time to sedatives correlated with anesthesia time. The standardized correlation coefficients were between 0.087 and 0.324. The anesthetic dose of fentanyl showed no correlation with each postoperative condition. Conclusions: Postoperative emergence time, extubation time, analgesia or sedation were demonstrated to be affected by anesthesia time, CPB time, age or fluid balance, however, because of the low correlation coefficients, it is suggested that each factor cannot independently affect postoperative patient care.
