Abstract
Transfusion-related acute lung injury (TRALI) is a life threatening adverse reaction to transfusion. It is characterized by noncardiogenic pulmonary edema developed during or within 6 hours after transfusion. Due to underrecognition of this complication, acute lung injury (ALI) after transfusion may be attributed to other causes such as allergic reaction, circulatory overload, or other risk factors. Recent study in the ICU of tertiary care medical center reveals high incidence of suspected TRALI cases. TRALI has relatively better prognosis as compared to ALI with other causes. Early diagnosis and intervention may improve the outcome of the patients with TRALI. Further study will elucidate the incidence and mechanisms of TRALI and the potential preventive measures.
