Abstract
We have experienced a case of a large floating thrombus in intact descending aorta. A 47-year-old woman was admitted to our hospital because of lumbago and claudication. Thoracoabdominal CT showed large mobile thrombus. She has no previous history of illness except for the lumbar compression fracture. We started anticoagulation therapy. At the 4th day after the admission, additional anticoagulation therapy with ticlopidine hydrochloride and sarpogrelate hydrochloride were started because of platelet increase in counts. At the 8th day, The CT showed regression of the thrombus and then we added the urokinase. The CT at the 23rd day revealed completely resolved thrombus. Thrombus formation in a morphologically normal aorta is rare. So we discussed the management.