Abstract
We report a 62-year-old female case of septic shock after percutaneous nephrolithotripsy (PNL). Because she developed hypotension, blood clotting abnormality, and respiratory failure on the next day, she was transferred to the ICU and diagnosed septic shock. She subsequently developed acute respiratory distress syndrome. We began respiratory support, and administered catecholamines and antibiotics. Her general condition recovered gradually and she was weaned from respiratory support on the 10th day. Septic shock after PNL is very rare and is caused by bacteria in the calculus and pyelovenous bacterial contamination due to the elevation of renal pelvis pressure. Although PNL is not so invasive, septic shock may happen, needing intensive care.