Abstract
The outcome of critical care includes not only physical recovery, but also psychological recovery. Neuropsychological issues such as post-traumatic stress disorder (PTSD) and neurocognitive impairment following intensive care are major issues impeding quality of life in patients. Recent studies have indicated that approximately 10% of the post-ICU patients have PTSD and related symptoms including intrusion, avoidance, and hyperarousal. Several studies have suggested that sedation management and delusional memory affect the development of PTSD symptoms. Neurocognitive impairment often occurs in patients following intensive care, although it is often unrecognized. Some evidence has suggested that delirium in the ICU is one of the risk factors of PTSD and neurocognitive impairment. Improvements in sedation management might play an important role in preventing these issues.