Abstract
We report a case of anaphylactic shock in patients on β-blockers. It was difficult to treat anaphylactic shock, and the patient lapsed into cardiopulmonary arrest. A 65-year-old man was stung by a bee and anaphylaxis caused fatal shock to him. Seven months ago, he had experienced acute myocardial infarction. During that hospitalization, treatment of β-blocker therapy was initiated. Intramuscular and intravenous injection of epinephrine were not effective. The patient lapsed into cardiopulmonary arrest after being carried into emergency room. Cardiopulmonary resuscitation and a large amount of epinephrine administration resulted in return of spontaneous circulation. It was considered that β-blocker drug that was medicated since hospital treatment affected epinephrine therapy. If anaphylaxis occurs in a patient receiving a β-blocker drug, it should be treated with increased dose epinephrine such as 2 to 5 times more at each injection than the usual dose of anaphylactic shock.
