Abstract
Heparin-induced thrombocytopenia (HIT) can develop due to the repeated administration of heparin after cardiovascular surgery, and therefore close attention must be paid. Surgical ascending aortic replacement was performed for an acute aortic dissection diagnosed by enhanced computed tomography. The patient received continuous hemodiafiltration (CHDF) and hemodialysis (HD) with the administration of nafamostat mesilate for acute renal failure after surgery. On post-operative day (POD) 11, nafamostat mesilate was changed to low molecular weight heparin during HD, and several hours after that, the patient suddenly fell into a state of shock. On POD 40, he was diagnosed with positive for HIT antibodies, suggesting that an administration of heparin during surgery may have led to the development of HIT and the repeated administration of heparin triggered the onset of a state of shock.
