Abstract
Human parechovirus (HPeV) infections exhibit various symptoms which are prone to becoming serious during the neonatal period and early infancy, causing septic shock or encephalopathy and possibly leading to death and/or serious neurologic aftereffects. We hereby report on our experience with two infant cases in which septic shock was caused from HPeV infection andintensive care management was required. The case 1 was a 1-month-old boy observed with septic shock, encephalopathy, and intestinal obstruction. Nine days of intensive care were required, including 7 days of respirator management. The case 2 was a 1-month-old boy observed with sepsis. Three days of intensive care were required. In these two cases, no apparent aftereffects were observed upon discharge from the hospital. HPeV infection in newborns and infants may become serious, causing aftereffects in the central nervous system; therefore, appropriate intensive care management and medium to long-term follow-up are necessary.