2014 Volume 21 Issue 5 Pages 487-492
The prevalence of cardiovascular morbidity and mortality is higher in patients with chronic kidney disease (CKD), especially those with end-stage renal disease, than in the general population. Congestive heart failure (CHF) is a representative cardiovascular disease. Although atherosclerotic coronary artery disease (≥75% stenosis) is the main cause of CHF, left ventricular hypertrophy and increased aortic stiffness may hasten the progress of myocardial ischemia in CKD patients with mild to moderate (<50%) coronary stenosis. Myocardial ischemia or CHF markedly increases the risk of sudden cardiac death (SCD) in patients with CKD. Finally, we review herein the data to support the use of pharmacologic and device-based therapies for the prevention of cardiovascular events including myocardial ischemia, CHF and SCD.
