A 4-year-old-boy diagnosed with catecholaminergic polymorphic ventricular tachycardia found after cardiac arrest

Abstract

A 4-year-old boy with no history or family history of related disease came to our hospital with cardiopulmonary arrest. He had fainted after running to the entrance of his home. After 30 minutes of cardiovascular resuscitation, circulation returned spontaneously. Polymorphic ventricular tachycardia and fibrillation were often seen and were suppressed by β-blockers, suggesting catecholaminergic polymorphic ventricular tachycardia (CPVT). No finding was made from resting electrocardiogram, except sinus bradycardia. Exercise electrocardiography was difficult for him because of his age. Two single nucleotide polymorphisms (SNPs) in calsequestrin 2 (CASQ2) confirmed the diagnosis.