Abstract
Objectives: Acute kidney injury (AKI) after cardiac surgery is associated with short- and long-term outcomes. The aim of this study was to investigate incidence rate, risk factors, and features of AKI after cardiac surgery with cardiopulmonary bypass (CPB). Methods: A single center retrospective study of postoperative AKI following cardiac surgery with CPB from 2011 to 2013 was performed. AKI in this study was defined as that which occurred within 7 days after surgery and diagnosed by the Acute Kidney Injury Network criteria. Results: A total of 263 patients met inclusion criteria. Of these 64 patients developed AKI, and two required dialysis within one week after the surgery. Multivariate analysis revealed that male sex (OR 4.20), diabetes mellitus (OR 3.34), increased body mass index (OR 1.11), a lower pre-operative estimated glomerular filtration rate (OR 0.963), and a longer CPB time (OR 1.01) were independent risk factors for AKI. Ninety-one-percent of AKI patients were classified into AKIN stage 1 and 78% were withdrawn from the AKI definition within 2 days after diagnosis. Conclusion: Except for male sex, the risk factors for AKI in this study were the same as in previous studies from the US and European countries. Most patients with AKI only presented a mild creatinine increase and recovered in a short period.
