Abstract
Objective: The aim of the study is to investigate the association of pre-, intra- and postoperative factors with the development of delirium after cardiovascular surgery. Methods: Expected factors for postoperative delirium were studied in 88 patients (65.6±11.9 years) underwent elective cardiovascular surgery. Hospital anxiety and depression scale (HADS), mini-mental state examination (MMSE), ability to perform activities of daily living and length of hospital stay before surgery were examined as preoperative factors of delirium. Body water balance during and after surgery, length of stay in an ICU and length of hospital stay after surgery were also monitored as intra- or postoperative factors. The presence of the delirium was assessed using the Japanese version of the CAM-ICU (confusion assessment method for the ICU). Results: Delirium was presented in 11 of 88 patients (12.5%). Patients with delirium showed statistically high HADS scores (P=0.003), low MMSE scores (P=0.031), large body water volume (P=0.030) and long ICU stay (P=0.022). Moreover, logistic analysis identified length of stay in ICU and HADS-depression scores as factors related to delirium after cardiovascular surgery. Conclusions: Our results suggested that high level of depression, low cognitive state and large body water volume were related to delirium after cardiovascular surgery.
