Abstract
Background: Re-expansion pulmonary edema (RPE) often occurs following minimally invasive cardiac surgery (MICS) involving differential lung ventilation. We investigated factors related to respiratory failure following MICS in our hospital. Methods: We included a total of 97 patients who had undergone MICS. Patients were divided into two groups by P/F ratio following surgical procedures of 4-6 hr: (1) high oxygenation group (group H, n=72, P/F ratio>300) and (2) low oxygenation group (group L, n=25, P/F ratio≤300). We compared these groups and investigated the related factors retrospectively. Results: One patient in group H and five patients in group L were diagnosed with RPE. In group L, preoperative albumin levels were low, differential lung ventilation time was long, and the volume of fresh frozen plasma (FFP) administered during surgery was high compared with the corresponding values in group H. Conclusion: Awareness of the potential occurrence of RPE should be kept in mind in the case of prolonged cardiac surgery or case with FFP transfusion.