Abstract
We demonstrate deep vein thrombosis (DVT) in three cases suspected by the increase in soluble fibrin monomer complex (SFMC) in plasma. In two cases, only SFMC increased while D-dimer and FDP did not change. Echoangiography of the femoral vein showed hemostasis and microthrombi in all cases. Measurement of SFMC may have greater clinical efficacy as a diagnostic test of early phase DVT than D-dimer in patients with clinical risk of DVT.