Abstract
We reported on the first verotoxin-producing Escherichia coli (VTEC): O-157 infection outbreak in a hospital in Japan. Ninety-one patients were infected with VTEC: O-157, of whom twenty-two had clinical symptoms. Three cases developed hemolytic uremic syndrome (HUS). Volume loading and diuresis were effective so that why no case needed hemodialysis (HD). Plasma exchange (PE) was performed due to impaired consciousness in the patient who needed HD, but the level of consciousness did not improve.