Ensho
Online ISSN : 1884-4006
Print ISSN : 0389-4290
ISSN-L : 0389-4290
Study on the relation between plasma prekallikrein (kallikrein) and protease inhibitors
Kikuo Takano
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JOURNAL FREE ACCESS

1981 Volume 1 Issue 2 Pages 263-268

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Abstract
I measured serum protease inhibitors, αl-antitrypsin, αl-antichymotrypsin, α2-macroglobulin, C 1 inactivator and inter-alpha-trypsin inhibitor by single radial immunodiffusion. I studied 15 normal controls and 52 patients with Behcet's disease.
In serum αl-antitrypsin, αl-antichymotrypsis, and inter-alpha-trypsin inhibitor showed an increase over normal controls, but the other protease inhibitors showed sligh increase.
A chromogenic sythetic tripeptide (Chrozym PK) was used as a substrate for kallikrein.
There was a tendency to low plasma kallikreinin in Behcet's disease. There was no correlation between plasma prekallikrein and CRP. The values of plasma kallikrein/ prekallikrein showed a sharp rise as plasma C 1 inactivator level was over about 40 mg/dl.
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© The Japanese Society of Inflammation and Regeneration
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