Abstract
Enlargement of the seminal vesicles (SV) and subjective pain are very important factors for the diagnosis of seminal vesiculitis. The relationship between enlargement of SV and pain was studied experimentally.
A total of 25 male Wistar rats weighing between 300 and 400 g were divided into 5 groups: control; saline injection; and 3 saline injection after pretreatment groups, consisting of intraluminal HCl washing of SV (chemical stimulation), compression with forceps of SV (physical stimulation) and intraperitoneal Aspirin DL-lysine injection, as the pretreatments. For the saline injection groups physiological saline was injected into SV at the speed of 1 and 2 ml/min through a tube placed in SV through a subcutaneous tunnel. Expression of pain was judged by an original criteria including twisting and turning of trunk and so on. No pain was observed in control group and group with analgesia. Pain was expressed in other 3 groups and was specially exaggerated in chemical and physical stimulation groups.
Thus the relationship between enlargement of SV and pain was proved.
