Abstract
Rubus suavissimus is a kind of the plants in Rosaceae, the leaves of which have been brewed and drunk as a usual drink in China. It has been experientially known that the tea is effective for sore throat and laryngitis.
In the present experiments, we investigated the influence of the Rubus suavissimus extracts on experimental allergy. As the results, the extracts showed the suppressive effects on cyclooxygenase activity and anaphylactically induced histamine release from rats peritoneal mast cells, in vitro. In addition to these, oral administration of the extracts significantly inhibited either skin reaction induced by compound 48/80 or passive cutaneous anaphylaxis in the rat.
These results suggest that the rubus suavissimus extracts are therapeutically effective for inflammatory and allergic diseases.
