Successful gammaglobulin therapy for reactive hemophagocytosis in pregnant woman with serological positive for anti-SS-A/-B antibody

Abstract

A 28-year-old pregnant woman who was serologically positive for anti-SS-A/-B antibody developed reactive hemophagocytosis, and gammaglobulin therapy was very effective in treating it. This case showed the underlying not only pregnancy but also disease such as some infections and serological abnormality. We suspect that the possible involvement of an immunological disorder of pregnancy in the pathogenesis of the hemophagocytosis.