Abstract
Bio-defense mechanism consists of various factors including antigen-specific immunities and non-specific factors. They express their functions to prevent the invasion of microorganisms or harmful substances into the tissue and to eliminate those in the tissue. Targets of bio-defense include a large number of substances of self- or nonself-origin. Thus, patterns of expression in the bio-defense are too much complex and then we need some new systems to compose such expression in systematized forms. In this paper, fundamental rules for understanding bio-defense and trials for clinical applications will be proposed.
