Effectiveness of Enoxaparin Sodium for Prophylaxis of Deep Vein Thrombosis After Surgery for Total Knee Arthroplasty — A Comparison of the Preventive Effect by the Starting Time of Administration

Abstract

 Anticoagulant medications have been widely used as prophylactic agents against deep vein thrombosis (DVT) in total knee arthroplasty. Yet, there are more factors we may need to consider when using such interventions including: drug selection, starting time, duration of administration and judgment of therapeutic effectiveness. In this study, we used enoxaparin sodium for prophylaxis of DVT, and examined the incidence rates of DVT from the time of commencing the drug administration.