Abstract
Since 1990 we have been doing trials using fibrin sealant for hemostasis at exposed cancellous bones in total knee replacement. We examined the difference in the volume of bleeding and frequency of blood transfusion between two groups. One was of 21 joints of TKR with which fibrin sealant was used and the other was of 44 joints of TKR with which it was not. The volume of intraoperative bleeding, the volume of postoperative bleeding, and the total volume of bleeding were significantly reduced in the fibrin sealant group. The frequency of blood transfusion was also significantly reduced in it. Based on the above results, we conclude that fibrin sealant is useful for hemostasis in total knee replacement.
