Mechanism of Aprotinin Injection Therapy on Herniated Discs Observed by Magnetic Resonance Imaging

Abstract

Fifteen cases of lumbar disc hernia were treated by aprotinin injection into the herniated disc. There was improvement of clinical symptoms in 11 (73%) of 15 patients. Most of the clinically improved group showed significant change in postoperative magnetic resonance imaging. This series suggested that a shape change of the protruding disc may have some relation to the mechanism of aprotinin injection therapy.