Abstract
We report an 11-year-old girl who despite having had no allergies, developed severe anaphylactic shock under general anesthesia on two occasions, and was diagnosed with latex allergy. The patient had undergone general anesthesia a total of five times by the age of 10 without any notable abnormalities. Retrograde urography was performed under general anesthesia for vesicoureteral reflux, but airway pressure increased 25 min after the injection of urography, and SpO2 became unmeasurable. Anaphylaxis was suspected, and the symptoms improved following adrenaline administration. Because the contrast agent was strongly suspected to be the cause of anaphylaxis, no further examination for identifying the allergen was performed. Fifteen months later, the patient again exhibited anaphylaxis when disimpaction was performed under general anesthesia for constipation, and the symptoms improved following adrenaline administration. Postoperative tests revealed that the patient's serum latex-specific IgE titer was positive strongly (class 6), and the patient was diagnosed with latex allergy. It is necessary in cases of intraoperative anaphylactic shock to consider latex allergy as a possible cause and to perform close examination. In addition, a latex-free environment should be established to prevent recurrence.
