Abstract
In parallel with the studies by Kobayashi of the authors' Department on the relationships between aromatic compounds and the adrenal gland (unpublished), the authors attempted to investigate the influence of histamine on the adrenalin in the adrenal grand. On this occasion, the authors also investigated the general development of chick embryo, the fluctuation in the amount of inorganic matters and the excretion of histamine in the .allantoic fluid in addition to the investigation of the amount of adrenalin in the abrenal gland. The results thus obtained are stated hereunder.
1) The chick embryo from the eggs added with histamine generally demonstrated a tendency of decrease in body weight. Particularly in the case when the eggs were treated with histamine of a high concentration, the general development of the chick embryo was evidently poor.
2) Among the cases treated with 15.0 mg of histamine, 1 case of pronounced edema was recognized.
3) No remarkable fluctuation in the amount of allantoic fluid of the chick embryo treated with histamine was noted.
4) The amount of adrenalin in the adrenal gland of the chick embryo treated with histamine was found increased.
5) The amount of Ca or Mg contained in the allantoic fluid of the chick embryo treated with histamine did not demonstrate any remarkable fluctuation.
6) The excretion of histamine in the allantoic fluid in the cases treated with histamine evidently demonstrated a tendency of increase when compared with the control cases treated with water.
