Abstract
Wistar albino female rats were poisoned by intraperitoneal administration of 50 mg/kg lead acetate after 48 hours' starvation, and they were hematologically observed to obtain the following results.
1) The hemoglobin concentration in the animals which were held under 48 hours' fasting remarkably fell by the administration of lead acetate, and its recovery of the normal level required an extremely long period of time.
2) The increase in the circulating reticulocytes after the administration of lead was. manifested later in the fasting animals.
3) The eisinopenic response due to the administration of lead acetate was significantly marked in the fasting animals.
Consequently, it could be concluded that starvation promoted the stressor effect of lead acetate, and inhibited the recovery from lead poisoning.
