Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
TRYPTOPHAN METABOLISM IN EXPERIMENTAL SCHISTOSOMIASIS
Tsuko Nakagome
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1958 Volume 18 Issue 6 Pages 559-562

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Abstract
1. Urinary excretion of tryptophan, kynurenine and anthranilic acid was measured in normal and infected mice with Schistosoma japonicum which were administered tryptophan prior to.
2. Excretion of tryptophan and anthranilic acid in urine decreased gradually during the course of infection. Kynurenine which was not found in control urine, however, appeared in infected mice.
3. Following intraperitoneal administration of tryptophan, urinary excretion of it and its metabolites increased in all stages of the infection.
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