Abstract
On investigating the uropepsin (U. P.) content of varying disorder, especially, gastric disorders, U. P. values were found to have a diagnostic value on gastric cancer and at the same time to give some valuable information for the treatment of various disorders, especially, gastric disorders.
1. U. P. values of cancerous disorders were mostly low, while those of ulcers were high with broader distribution. Patients of gastritis sometimes showed low values with fairly broad distribution. Patients of appendicitis were divided into two group of low and high U. P. values. Mild cases of pulmonary tuberculosis, moreover, were found to have broad distribution. Accordingly, U. P. values were found to be valuable not as a measure for differential diagnosis but as that of knowing the clinical status of individual patient.
2. In the patients of gastric disorders, gastric pepsin (G. P.) changes in parallel to U. P. in most cases, but in some cases it does not, which might probably due to the influence of adrenal functions and such cases were the patients of gastric cancer or ulecr.
3. Gastric acidity has a lesser degree of parellel relationship to the U. P. content than it does to G. P. Most cases showing nearly no pararellism.
4. Those who showed abnormality in Thorn Test possessed low U. P. values and those without any parallelism between G. P, and U. P. were found to have some disorders of the adrenal functions. Thorn Test abnormal cases were predominant among the patients of gastric cancer.
5 In contrast to appendectomy, U. P. values after gastrectomy show larger increase for longer period. No specific tendency was recognized, however, on the appearance of the peak of this increese. Patients of cancerous disorders showed small deviation in U. P. values.
