Abstract
Further investigations were made on the pharmacology of S-benzoylthiamine O-monophosphate (BTMP) and the results obtained were as follows:
Intracisternal injection of BTMP in a dose of 2.5-5.0 mg/kg produces the excitement of respiration and the increase of blood pressure.
In the rabbit, BTMP solution above the concentration of 10-3 gives an inhibitory influence on the auricles of the heart.
In the rabbit, intravenous injection of BTMP gives no influence on the body temperature but gives a diuretic action.
Absorption of BTMP from the large intestine by enema is good.
