Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
INFLUENCE OF SODIUM GLUCURONATE ISONICOTINYL HYDRAZONE (INHG) AND ISONICOTINIC ACID HYDRAZIDE (INAH) ON CHICK EMBRYOS HYCRAZONE
Asao Ozawa
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1960 Volume 20 Issue 9 Pages 1189-1200

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Abstract
On comparison of the mortality of chick embryos between INHG and INAH, the toxicity of INHG was found to be lower than that of INAH and the growth inhibition due to the administration of INAH was found to be moderated by its administration in the form of INHG. On quantitative determination of INAH contained in the allantoic fluid, in either case of the administration of INAH or INHG, the amount of excretion was found to increase following the increase in the dose administered and the maximum excretion during the course of incubation was observed in the middle stage. Increase in the hepatic weight was better among the embryos administered of INHG than those received INAH but the amount of INAH contained in the liver was larger among the embryos administered of INAH than those received INHG.
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