Abstract
Amounts of urinaly allantoin and creatinine after total bcdy irradiation were measured by means of rat experiment.
1) The creatinine excretion was well correlated to the body weight of the animal (r=0.754) . Daily excretion was 52.4±2.7γ per gram of the body weight.
The amount decreased significantly on the 3 rd day after irradiation and returned to the normal level on the 6 th day; cysteine pre-treatment seemed to have no influence upon this course.
2) The allantoin excretion was also correlated to the body weight of the animal (r=0.617) . Daily excretion was 249.2±26.3γ per gram weight of the animal.
The amount increased significantly on the 1 st day after irradiation, then decreased from the 3 rd day until returned to the normal on the 6 th day. No increase was observed in the cystein pre-treated rat. However, the decrease was more remarkable than those in the rat not pre-treated.
3) Allantoin-creatinine ratio was 4.82±0.40 in the control animal. This ratio increased on the 1 st day after irradiation, then decreased on the 2 nd and 3 rd day. The peak of this ratio might be an indication of injury soon after irradiation.
