無脳児妊娠6例とその母児におけるエストロゲンについて

鈴木 仁一; 野嶽 幸正; 久保田 仁; 真鍋 美智雄; 杉崎 賢三; 目時 信之; 上原 一浩; 荒木 日出之助; 張 相天; 黒田 惇

doi:10.14930/jsma1939.31.108

SIX CASES OF ANENCEPHALUS AND THE MATERNAL AND FETAL ESTROGENS

Jinichi Suzuki, Yukimasa Notake, Hitoshi Kubota, Michio Manabe, Kenzo Sugizaki, Nobuyuki Metoki, Kazuhiro Uehara, Hidenosuke Araki, Soien Cho, Jun Kuroda

Author information

Jinichi Suzuki
Department of Obstetrics and Gynecology, School of Medicine, Showa University
Yukimasa Notake
Department of Obstetrics and Gynecology, School of Medicine, Showa University
Hitoshi Kubota
Department of Obstetrics and Gynecology, School of Medicine, Showa University
Michio Manabe
Department of Obstetrics and Gynecology, School of Medicine, Showa University
Kenzo Sugizaki
Department of Obstetrics and Gynecology, School of Medicine, Showa University
Nobuyuki Metoki
Department of Obstetrics and Gynecology, School of Medicine, Showa University
Kazuhiro Uehara
Department of Obstetrics and Gynecology, School of Medicine, Showa University
Hidenosuke Araki
Department of Obstetrics and Gynecology, School of Medicine, Showa University
Soien Cho
The 1st Department of Pathology, School of Medicine, Showa University
Jun Kuroda
The 1st Department of Pathology, School of Medicine, Showa University

JOURNAL FREE ACCESS

1971 Volume 31 Issue 2 Pages 108-113

DOI https://doi.org/10.14930/jsma1939.31.108

Details

Abstract

Recently, six cases of anencephalus were experienced.
The adrenal cortex of anencephalus was hypoplastic and the weight was about tenth of the normal baby. Luck of the anterior pituitary was observed Study of anencephalus is, important to clarify the mechanism of biosynthesis of estrogens. Urine of two cases of anencephalus pregnant women were analyzed for estrogens and plasma of other two cases were analyzed for estriol. Urinary estrogen level of anencephalus was lower than that of normal pregnancy. Urinary estriol concentration was 3.9 per cent of normal pregnancy. Plasma estriol concentration of anencephalus was about ten per cent of normal pregnancy but the ratio of the maternal antecubital vein and the umbirical vessels was equal to that of normal pregnancy.

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