Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
ON A FEW OF EFFECTS OF LIVER PROTECTING AGENTS FOR BONE MARROW AND LIVER FUNCTION IN LIVER INJURY
Hideo Shimura
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1972 Volume 32 Issue 5 Pages 258-264

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Abstract
That the bone marrow gets purine from liver has been claimed by Lajtha. 2-mercap-topropionyl-glycine (MPG), containing SH in the molecule is expected to protect the liver from radiation damage given prior to liver irradiation. However, that liver disorders of various kinds have been ameliorated by MPG has a good reason the drug to ameliorate radiation-induced liver disorder though given after irradiation.
Some experiments were carried out and following results were obtained. Decreased DNA synthetic rate in bone marrow and prolonged BSP clearance rate after liver irradiation were improved by MPG administration.
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© The Showa Medical Association
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