Abstract
The 61 year old woman suffered from chronic myeloid leukemia was treated with busulf an and splenic irradiation since April 1970.
Almost 3 years later, tender tumor of thumb-tip size appeared in her right temporal area.
Although she had no evidence for blastic transformation in hematological examination, combined therapy with 6-mercaptopurine, busulf an and prednisolone were performed.
However, the enlargement of the tumor was developed and she died of apoplectic attack on February 1973.
At postmortem examination, the tumor was myeloblastoma 5×5 cm in size which de-stroyed the temporal bone and compressed the temporal lobule with infiltration of tumor cells.
A review of the previously reported cases in literature was made.