Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
A CASE OF CHRONIC MYELOID LEUKEMIA WITH INTRACRANIAL TUMOR IN TERMINAL PHASE
Shin SanoTatsuaki NozuMorimasa IshibashiShigeyoshi OguriHidekazu OtaNorimasa SakamotoKenichiro KonoNobuyoshi TsuruokaToshio Morohoshi
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1976 Volume 36 Issue 1 Pages 63-70

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Abstract
The 61 year old woman suffered from chronic myeloid leukemia was treated with busulf an and splenic irradiation since April 1970.
Almost 3 years later, tender tumor of thumb-tip size appeared in her right temporal area.
Although she had no evidence for blastic transformation in hematological examination, combined therapy with 6-mercaptopurine, busulf an and prednisolone were performed.
However, the enlargement of the tumor was developed and she died of apoplectic attack on February 1973.
At postmortem examination, the tumor was myeloblastoma 5×5 cm in size which de-stroyed the temporal bone and compressed the temporal lobule with infiltration of tumor cells.
A review of the previously reported cases in literature was made.
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© The Showa Medical Association
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