Abstract
It was studied that rabbit lung lesions and that cross-reactivities between lung tissue and microorganismus, e.g., Strept. haemolyticus, Kleb. pneumoniae, E. coli, Clost. welchii and Entero. faecalis
The results were as follows;
1) In rabbit immunized with the disrupted bacteria, it was observed the marked granulomatous lesions with epitheloid cells, lymph cells and giant cells
2) On fluorescent antibody technique, the specific stainings were found at the lung and heart by the anti-Clost. welchii sera and at the kidney by the anti-Strept. haemolyticus sera
3) Auto-antibodies (anti-lung antibodies) were observed in anti-rabbit sera immunized with Kleb. pneumoniae and Entero. faecalis.
4) In passive haemoagglutination and inhibition test, there was some cross-reactivity between lung tissue and Entero. faecalis.
5) Rheumatoid factor-like substances were found in all anti-rabbit sera immunized each microrogranismus.