Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
STUDIES ON THE ALLERGY OF UPPERRESPIRATORY AND ENTEROFLORA
INDUCTION OF SARCOID LIKE LESIONS IN THE LUNG
Akira Murakoshi
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JOURNAL FREE ACCESS

1976 Volume 36 Issue 3 Pages 213-221

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Abstract
It was studied that rabbit lung lesions and that cross-reactivities between lung tissue and microorganismus, e.g., Strept. haemolyticus, Kleb. pneumoniae, E. coli, Clost. welchii and Entero. faecalis
The results were as follows;
1) In rabbit immunized with the disrupted bacteria, it was observed the marked granulomatous lesions with epitheloid cells, lymph cells and giant cells
2) On fluorescent antibody technique, the specific stainings were found at the lung and heart by the anti-Clost. welchii sera and at the kidney by the anti-Strept. haemolyticus sera
3) Auto-antibodies (anti-lung antibodies) were observed in anti-rabbit sera immunized with Kleb. pneumoniae and Entero. faecalis.
4) In passive haemoagglutination and inhibition test, there was some cross-reactivity between lung tissue and Entero. faecalis.
5) Rheumatoid factor-like substances were found in all anti-rabbit sera immunized each microrogranismus.
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© The Showa Medical Association
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