TWO CASES OF MULTIPLE PRIMARY CARCINOMAS INVOLVING BREAST CARCINOMA

Abstract

A review was made about 286 cases of breast carcinomas, which were operated at our hospital during past 21 years. Two instances of multiple primary carcinomas were found in this group. These two cases were statisfied with the criteria of Warren & Gates and histologically, each case of them showed a dissimilar pattern. These cases are presented as follows:
Case 1. The patient was a woman, aged 57 years. A radical mastectomy had been performed elsewhere in 1966 for adenocarcinoma (medullary tubular carcinoma) of the right breast. In 1974 she was diagnosed as a carcinoma of the esophagus and endoscopically biopsied specimen of the esophageal lesion was proved squamous cell carcinoma. Because of an unresectable case, By-pass operation performed conservatively. 2 months after the second operation she died from cachexy.
Case 2. The patient was a woman, aged 58 years. In November, 1953, a mass was found in the left thyroid gland and remained untreated after conservative therapy for 2 months. The mass had enlarged gradually. In March, 1958, a mass was found in the left breast and she admitted to performed the operation on carcinomas of the left breast and of the thyroid gland. Immediately after admission, a radical mastectomy and a conservative left lobectomy of the thyroid gland were done. Histologically, the breast lesion showed medullary tubular adenocarcinoma and the lesion of the thyroid gland showed papillary-follicular adenocarcinoma. 7 years after the operation she died from the local recurrence of the carcinoma of the thyroid gland.