Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
ANESTHETIC MANAGEMENT OF A PATIENT ON LEVODOPA THERAPY
Kenji MochimaruShohei TakedaKen-ichi KagamiMasanao Shibuya
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1979 Volume 39 Issue 6 Pages 681-684

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Abstract
A 70-year-old female patient was admitted to the hospital because of fracture of the right hip. The patient had a history of Parkinson's disease. The patient had been receiving levodopa 0.2 g three times daily. The last dose of levodopa was 72 hours before surgery. Premedication was atropine sulphate 0.4mg given one hour preoperatively. Anesthetic induc-tion was with diazepam-succinylcholine chloride followed by tracheal intubation. Anesthesia was then maintained with N2 0-02 (3 : 1.5 litres) . The patient's cardiovascular status was almost stable during the operation. Postoperative course was uneventful. Levodopa was readministrated 72 hours after the operation. Some anesthetic agents may cause cardiovascular complication. Therefore, careful and sufficient attention must be given if a patient has been treated with levodopa therapy.
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