A CASE OF GARDNER SYNDROME

Abstract

Gardner's syndrome (a familial disease, characterized by colonic polyposis, osteoma and soft tissue tumor) was categorized by Gardner (1950) . To the best of our knowlage, 14 cases of this disease were reported in Japan. A case of 28-year-old man of Gardner's syndrome was presented. He was admitted with complaints of gastric discomfort, abdominal pain and diarrhea. Gastrointestinal endoscopiy and X-ray examination showed colonic polyposis, gastric polyposis and osteosclerotic change of the right mandibles bone, no tumor was found in soft tissue. Total resection of the colon was performed. Colectomized specimen showed ulcerated lesions in transvers colon and diffuse polyposis. It was demonstrated that the ulcerated lesions was adenocarcinoma and diffuse polyposis were adenomatous polyp, histologically differentiation of Gardner's syndrome from familial polyposis coli was discussed.