Abstract
Gastric secretory responses to tetra-gastrin, serum gastrin, insulin and IgE concentration were investigated in 50 patients with peptic ulcers (40 cases of gastric ulcers and 10 of duodenal ulcers) . In patients with active ulcers, gastric secretion levels were greater in recurrent cases than in cases of initial onset. Pepsin output was higher in the old than in the middle-aged. Serum gastrin concentration was within a normal range in cases with duodenal ulcers, while it was a higher than normal range (140 pg/ml) in 8 cases of gastric ulcer. And, gastrin concentration was detected at a higher level in ulcers of the mid- and under-stomach as compared to that of the upper stomach. The serum insulin concentration was in a higher than normal range (20μμ/ml) in 23 cases of peptic ulcers (20 cases of gastric ulcer and 3 of duodenal ulcer) . A higher than normal (1000 I. U./ml) serum IgE concentration was not de-tected. The IgE value was, however, higher in recurrent cases than in those of initial ulcer onset.
